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(Phenylamino)ethanethioic acid S-1H-benzimidazol-2-yl ester, also known as benzimidazole-2-thione, is a chemical compound widely utilized in the pharmaceutical industry. It serves as a reagent in the synthesis of various organic compounds and functions as a ligand in coordination chemistry. Benzimidazole-2-thione has garnered attention for its potential biological activities, such as antimicrobial, antiviral, and anticancer properties, as well as its inhibitory effects on enzymes like tyrosinase and HIV reverse transcriptase. Its diverse nature and potential therapeutic applications make benzimidazole-2-thione a subject of ongoing scientific research and drug development.

83408-76-8

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83408-76-8 Usage

Uses

Used in Pharmaceutical Industry:
Benzimidazole-2-thione is used as a reagent for the synthesis of various organic compounds, contributing to the development of new pharmaceuticals and therapeutic agents.
Used in Coordination Chemistry:
As a ligand, benzimidazole-2-thione is employed in coordination chemistry to form complexes with metal ions, which can have potential applications in various fields, including catalysis and material science.
Used in Antimicrobial Applications:
Benzimidazole-2-thione is used as an antimicrobial agent, leveraging its ability to inhibit the growth of microorganisms, which can be beneficial in treating infections and developing antimicrobial products.
Used in Antiviral Applications:
(Phenylamino)ethanethioic acid S-1H-benzimidazol-2-yl ester is utilized as an antiviral agent, targeting viruses such as HIV by inhibiting key enzymes like reverse transcriptase, thereby suppressing viral replication and reducing the spread of infection.
Used in Anticancer Applications:
Benzimidazole-2-thione is studied for its potential as an anticancer agent, with research exploring its ability to target and inhibit the growth of cancer cells, offering a promising avenue for cancer treatment and therapy development.
Used in Enzyme Inhibition:
(Phenylamino)ethanethioic acid S-1H-benzimidazol-2-yl ester is used to inhibit enzymes such as tyrosinase, which is involved in melanin production, and HIV reverse transcriptase, playing a role in the regulation of pigmentation and the treatment of HIV infections, respectively.

Check Digit Verification of cas no

The CAS Registry Mumber 83408-76-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,4,0 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 83408-76:
(7*8)+(6*3)+(5*4)+(4*0)+(3*8)+(2*7)+(1*6)=138
138 % 10 = 8
So 83408-76-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H13N3OS/c19-14(10-16-11-6-2-1-3-7-11)20-15-17-12-8-4-5-9-13(12)18-15/h1-9,16H,10H2,(H,17,18)

83408-76-8Downstream Products

83408-76-8Relevant academic research and scientific papers

Synthesis and CNS Activity of 2-(N-Arylaminoacetylmercapto)- and 2-(N-Arylacetamidomercapto)-benzimidazoles

Tripathi, Shephali,Ahmad, Shakeel,Barthwal, J. P.,Kishor, K.,Tangri, K. K.,Bhargava, K. P.

, p. 379 - 380 (2007/10/02)

The title mercaptobenzimidazoles (1a-t) have been synthesised and screened for their anticonvulsant and monoamine oxidase (MAO) inhibitory activities.Some of the compounds provide 80percent protection against pentylenetetrazole-induced convulsions and max

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