83410-38-2 Usage
Uses
Used in Pharmaceutical Industry:
5-Bromo-2-methylpyrimidine-4-carboxylic acid ethyl ester is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to be readily modified and incorporated into complex molecular structures. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Bromo-2-methylpyrimidine-4-carboxylic acid ethyl ester is utilized as a starting material for the creation of novel agrochemicals, such as pesticides and herbicides. Its reactivity and structural properties enable the design of effective compounds that can target specific pests or weeds, thereby increasing crop yields and protecting agricultural investments.
Used in Medicinal Chemistry Research:
5-Bromo-2-methylpyrimidine-4-carboxylic acid ethyl ester serves as a valuable research tool in medicinal chemistry. It is used for exploring the structure-activity relationships of pyrimidine-based compounds, aiding in the discovery of new therapeutic agents with improved efficacy and selectivity.
Used in Organic Synthesis:
As a building block in organic synthesis, 5-Bromo-2-methylpyrimidine-4-carboxylic acid ethyl ester is employed for the preparation of a wide range of organic compounds. Its high reactivity allows for various chemical reactions, facilitating the synthesis of complex organic molecules for use in different industries, including materials science and specialty chemicals.
Used in Chemical Research and Development:
In the realm of chemical research and development, 5-Bromo-2-methylpyrimidine-4-carboxylic acid ethyl ester is leveraged for the investigation of new reaction pathways and the development of innovative synthetic methods. Its unique properties make it an attractive candidate for advancing the field of organic chemistry and expanding the scope of synthetic capabilities.
Check Digit Verification of cas no
The CAS Registry Mumber 83410-38-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,4,1 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 83410-38:
(7*8)+(6*3)+(5*4)+(4*1)+(3*0)+(2*3)+(1*8)=112
112 % 10 = 2
So 83410-38-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H9BrN2O2/c1-3-13-8(12)7-6(9)4-10-5(2)11-7/h4H,3H2,1-2H3
83410-38-2Relevant academic research and scientific papers
Structure-based design and synthesis of bicyclic fused-pyridines as MEK inhibitors
Lu, Hejun,Tu, Wangyang,Fei, Hongbo,Xu, Guoji,Hu, Qiyue,Zhang, Lei,Lin, Bing,Yuan, Jijun,Yin, Junzhao,Gong, Aishen,Wan, Mimi,Wang, Dan,Zhu, Xiaoyan,Feng, Jun,Wang, Qian,Sun, Piaoyang
, p. 2555 - 2559 (2014/05/20)
The MAPK pathway is identified as one of the most important pathways involved in cell proliferation and differentiation. A key kinase in the pathway, the Mitogen-activated protein kinase kinase (MEK) is recognized as a promising target for antitumor drugs. Structure-based design and optimization of known MEK inhibitors resulted in identification of compound 10a as a potent non-ATP competitive MEK inhibitor in both in vitro and in vivo tests.
A facile synthesis of 5-halopyrimidine-4-carboxylic acid esters via a Minisci reaction
Regan, Collin F.,Pierre, Fabrice,Schwaebe, Michael K.,Haddach, Mustapha,Jung, Michael E.,Ryckman, David M.
experimental part, p. 443 - 447 (2012/03/11)
This paper reports the synthesis of various 5-halopyrimidine-4-carboxylic acid esters via the Minisci homolytic alkoxycarbonylation of 5-halopyrimidines. The reaction was found to be highly regioselective, allowing the one-step synthesis of useful amounts
