834154-88-0Relevant academic research and scientific papers
Cyclization of 3-ethoxycarbonylmethyl-, 3-cyanomethyl-, and 3-acetylmethyl-1-amino-2-methylbenzimidazolium salts effected by acetic anhydride in the presence of a base
Kuz'menko,Kuz'menko,Anisimova
, p. 221 - 227 (2004)
3-Ethoxycarbonylmethyl- and 3-cyanomethyl-1-amino-2-methylbenzimidazolium chlorides cyclized at treatment with acetic anhydride in the presence of potassium carbonate to afford a mixture of derivatives of pyrazolo[1,5-a] benzimidazole and 4-aminopyrrolo[1,2-a]benzimidazole. Therewith in the first case prevails the process of pyrazole ring fusion, and in the latter pyrrole ring is fused. 3-Aroyl(thenoyl)methyl-1-amino-2-methylbenzimidazolium bromides under the same conditions are converted into 1-aroyl(thenoyl)-2-methyl- and 2-4-acetamido-3-acetylpyrrolo[1,2-a]benzimidazoles.
