83443-69-0 Usage
Uses
Used in Pharmaceutical Development:
Methyl 3-(2-oxo-2H-pyrimido[2,1-b][1,3]benzothiazol-4-yl)prop-2-enoate is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure, including the benzothiazole-pyrimidine fusion and functional groups, makes it a promising candidate for the development of new drugs with potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, methyl 3-(2-oxo-2H-pyrimido[2,1-b][1,3]benzothiazol-4-yl)prop-2-enoate serves as a valuable research tool for studying the structure-activity relationships of related heterocyclic compounds. Its synthesis and modification can provide insights into the design of novel therapeutic agents with improved efficacy and selectivity.
Used in Drug Discovery:
Methyl 3-(2-oxo-2H-pyrimido[2,1-b][1,3]benzothiazol-4-yl)prop-2-enoate is employed in drug discovery processes to identify potential lead compounds with biological activity. Its heterocyclic core and functional groups can be optimized to enhance interactions with biological targets, leading to the development of new therapeutic agents.
Used in Chemical Synthesis:
methyl 3-(2-oxo-2H-pyrimido[2,1-b][1,3]benzothiazol-4-yl)prop-2-enoate is also used as a building block in the synthesis of more complex organic molecules. Its reactivity and structural features make it suitable for various synthetic routes, contributing to the creation of new chemical entities with diverse applications.
Used in Biochemical Studies:
Methyl 3-(2-oxo-2H-pyrimido[2,1-b][1,3]benzothiazol-4-yl)prop-2-enoate can be utilized in biochemical studies to investigate its interactions with enzymes, receptors, or other biological macromolecules. Understanding these interactions can provide valuable information for the development of targeted therapies and diagnostic tools.
Check Digit Verification of cas no
The CAS Registry Mumber 83443-69-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,4,4 and 3 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 83443-69:
(7*8)+(6*3)+(5*4)+(4*4)+(3*3)+(2*6)+(1*9)=140
140 % 10 = 0
So 83443-69-0 is a valid CAS Registry Number.
83443-69-0Relevant academic research and scientific papers
Products from Dimethyl Hex-2-en-1-yne-1,6-dioate and Dimethyl Penta-2,3-diene-1,5-dioate with Compounds possessing Two Adjacent Nucleophilic Centers
Acheson, R. Morrin,Wallis, John D.
, p. 1905 - 1914 (2007/10/02)
Thiuoreas and thioamides were found to add via sulphur to position 5 of dimethyl hex-2-en-4-yne-1,6-dioate; often this was followed by cyclisation to give γ-lactams.In some cases cis-addition was observed as well as trans-addition, even in methanol.Imidazoline-2-thione and benzimidazole-2-thione also reacted at position 4 to give fused thiazinone derivatives. 2-Amino-benzothiazole, -thiazole, and -pyridine all added via the ring nitrogen to position 4, and subsequent cyclisation gave fused pyrimidones. 1,2-Diaminobenzene and 2-aminobenzenethiol reacted like the thioureas at position 5, but addition to position 4 was followed by a further Michael addition to position 3.These benzene derivatives reacted with dimethyl penta-2,3-diene-1,5-dioate to give cyclic compounds with exocyclic unsaturated ester groups.In contrast, thioureas reacted with the allene to give derivatives of methyl 4-oxothiazin-6-ylacetate.Structures of the new compounds were deduced from their 1H and 13C n.m.r., u.v., i.r., and mass spectra.
