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834894-21-2

PF-562771 is a potent and selective small molecule inhibitor of FAK (focal adhesion kinase), a non-receptor tyrosine kinase that plays a crucial role in cell adhesion, migration, and proliferation. It effectively inhibits FAK activity in cancer cells, leading to decreased cell proliferation and increased cell death. PF-562771 also suppresses the phosphorylation of focal adhesion complexes and disrupts the formation of stress fibers, ultimately inhibiting the migration and invasion of cancer cells. It demonstrates potential as a therapeutic agent for various cancers by targeting FAK-dependent signaling pathways involved in tumor progression and metastasis.

834894-21-2

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834894-21-2 Usage

Uses

Used in Pharmaceutical Industry:
PF-562771 is used as an anticancer agent for its ability to inhibit FAK activity, leading to decreased cell proliferation and increased cell death in cancer cells. It targets FAK-dependent signaling pathways involved in tumor progression and metastasis, making it a promising candidate for the treatment of various cancers.
Used in Cancer Research:
PF-562771 is used as a research tool for studying the role of FAK in cancer cell adhesion, migration, and proliferation. Its ability to inhibit FAK activity and disrupt cancer cell migration and invasion provides valuable insights into the molecular mechanisms underlying cancer progression and metastasis.
Used in Drug Development:
PF-562771 is used as a lead compound in the development of novel therapeutic agents targeting FAK for the treatment of various cancers. Its selectivity and potency in inhibiting FAK activity make it a valuable starting point for the design and optimization of new drugs with improved efficacy and safety profiles.
Used in Combination Therapy:
PF-562771 is used in combination with other anticancer agents to enhance the therapeutic effects and overcome drug resistance in cancer treatment. Its ability to inhibit FAK activity and disrupt cancer cell migration and invasion can potentially synergize with other treatments, leading to improved outcomes in cancer patients.

Check Digit Verification of cas no

The CAS Registry Mumber 834894-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,4,8,9 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 834894-21:
(8*8)+(7*3)+(6*4)+(5*8)+(4*9)+(3*4)+(2*2)+(1*1)=202
202 % 10 = 2
So 834894-21-2 is a valid CAS Registry Number.

834894-21-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name PF-562771

1.2 Other means of identification

Product number -
Other names AP 23848

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:834894-21-2 SDS

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