83494-25-1 Usage
Description
1-(3-nitrophenyl)prop-2-yn-1-ol is a chemical compound with the molecular formula C9H7NO3. It is an organic compound characterized by the presence of a nitro group and an alkyne functional group attached to a phenyl ring. 1-(3-nitrophenyl)prop-2-yn-1-ol is known for its versatility in organic synthesis and its utility as a substrate in various chemical reactions.
Uses
Used in Organic Synthesis:
1-(3-nitrophenyl)prop-2-yn-1-ol is used as a key intermediate in organic synthesis for the creation of a wide range of chemical products. Its unique structure allows for multiple reaction pathways, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-(3-nitrophenyl)prop-2-yn-1-ol serves as a building block for the development of new drugs. Its ability to be transformed into various products through chemical reactions contributes to its importance in medicinal chemistry, aiding in the discovery and production of novel pharmaceuticals.
Used in Chemical Reactions as a Substrate:
1-(3-nitrophenyl)prop-2-yn-1-ol is utilized as a substrate in a variety of chemical reactions. Its reactivity, stemming from the presence of the nitro and alkyne groups, allows it to participate in numerous chemical processes, which is crucial for the advancement of organic chemistry.
Overall, 1-(3-nitrophenyl)prop-2-yn-1-ol is a significant compound in the field of organic chemistry due to its diverse applications and the potential for further chemical transformations, which can lead to the development of new and innovative products across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 83494-25-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,4,9 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 83494-25:
(7*8)+(6*3)+(5*4)+(4*9)+(3*4)+(2*2)+(1*5)=151
151 % 10 = 1
So 83494-25-1 is a valid CAS Registry Number.
83494-25-1Relevant articles and documents
A sustainable access to ynones through laccase/TEMPO-catalyzed metal- and halogen-free aerobic oxidation of propargylic alcohols in aqueous medium
Silva, Alana B.V.,Silva, Emmanuel D.,dos Santos, Alcindo A.,Princival, Jefferson L.
, (2020/02/04)
Tuning laccase/TEMPO-catalyzed aerobic oxidation of secondary propargylic alcohols in aqueous media was accomplished in order to efficiently synthesize ynones. This study led to the formulation of an effective and sustainable catalytic method for the preparation of mono- and bis-substituted ynones compared with traditional oxidative methods.
Stereoselective, Cascade Synthesis of trans-Enynones through Coupling-Isomerization Reaction
Chinta, Bhavani Shankar,Baire, Beeraiah
, p. 10208 - 10217 (2015/11/03)
A mild, cascade methodology based on the modified Cadiot-Chodkiewicz reaction was developed for the stereoselective synthesis of trans-enynones. By this methodology, structurally divergent trans-enynones, which are embedded with sensitive functional groups, were synthesized. Control experiments suggested that the CuCl alone does not have a role in the isomerization step, whereas the CuCl-piperidine complex (formed during the cross coupling) may have a rate enhancing effect. Furthermore, additional sets of control experiments favor the involvement of unimolecular [1,2]-H shift rather than a homobimolecular proton abstraction during the isomerization step.
4- AND 5-ALKYNYLOXINDOLES AND 4- AND 5-ALKENYLOXINDOLES
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Page/Page column 39, (2010/02/04)
4- and 5-alkynyloxindoles as well as 4- and 5-alkenyloxindoles having formula (I) and (II), wherein R, R, R, R, R, X and z have the meaning indicated in the specification, inhibit or modulate protein kinases, in particular JNK protein kinases and are useful as anti-inflammatory agents, particularly in the treatment of rheumatoid arthritis.
