83501-10-4Relevant articles and documents
A convenient synthesis of 5- and 6-substituted 2-phenyl-3H-pyrimidin-4-ones
Zanatta, Nilo,Fantinel, Leonardo,Lourega, Rogerio V.,Bonacorso, Helio G.,Martins, Marcos A. P.
, p. 358 - 362 (2008/09/20)
A simple and convenient one-pot procedure for the synthesis of 5- and 6-substituted 2-phenyl-3H-pyrimidin-4-ones by the condensation of 4-alkoxy-1,1,1-trichloroalk-3-en-2-ones with benzamidine hydrochloride is described. Georg Thieme Verlag Stuttgart.
1,3-Oxazines and Related Compounds. VI. Synthesis and Some Reactions of 2,6-Disubstituted 4H-1,3-Thiazin-4-ones
Yamamoto, Yutaka,Ohnishi, Shuhei,Azuma, Yutaka
, p. 1929 - 1935 (2007/10/02)
Various of 2,6-disubstituted 4H-1,3-thizin-4-ones (5) were synthesized by successive treatment of N-acylacetylcarboxamides with acid (such as 70percent perchloric acid or fluorosulfonic acid) and hydrogen sulfide.Reactions of 5 were investigated; ammonolysis with ethanolic ammonia gave the corresponding pyrimidin-4-ones; hydrolysis of 2-alkyl-1,3-thiazine derivatives yielded ring-opend N-acyl-β-mercaptocrotonamides; reduction with NaBH4 or LiALH4 afforded 3,4-dihydro-2H-1,3-thiazin-4-one derivatives.Keywords - 1,3-thiazin-4-one; 3,4-dihydro-2H-1,3-thiazin-4-one; pyrimidin-4-one; 1,3-oxazinium salt; 1,3-thiazinium salt; N-acylacetylcarboxamide; N-acyl-β-mercaptocrotonamide