83501-10-4Relevant academic research and scientific papers
A convenient synthesis of 5- and 6-substituted 2-phenyl-3H-pyrimidin-4-ones
Zanatta, Nilo,Fantinel, Leonardo,Lourega, Rogerio V.,Bonacorso, Helio G.,Martins, Marcos A. P.
, p. 358 - 362 (2008/09/20)
A simple and convenient one-pot procedure for the synthesis of 5- and 6-substituted 2-phenyl-3H-pyrimidin-4-ones by the condensation of 4-alkoxy-1,1,1-trichloroalk-3-en-2-ones with benzamidine hydrochloride is described. Georg Thieme Verlag Stuttgart.
1,3-Oxazines and Related Compounds. VI. Synthesis and Some Reactions of 2,6-Disubstituted 4H-1,3-Thiazin-4-ones
Yamamoto, Yutaka,Ohnishi, Shuhei,Azuma, Yutaka
, p. 1929 - 1935 (2007/10/02)
Various of 2,6-disubstituted 4H-1,3-thizin-4-ones (5) were synthesized by successive treatment of N-acylacetylcarboxamides with acid (such as 70percent perchloric acid or fluorosulfonic acid) and hydrogen sulfide.Reactions of 5 were investigated; ammonolysis with ethanolic ammonia gave the corresponding pyrimidin-4-ones; hydrolysis of 2-alkyl-1,3-thiazine derivatives yielded ring-opend N-acyl-β-mercaptocrotonamides; reduction with NaBH4 or LiALH4 afforded 3,4-dihydro-2H-1,3-thiazin-4-one derivatives.Keywords - 1,3-thiazin-4-one; 3,4-dihydro-2H-1,3-thiazin-4-one; pyrimidin-4-one; 1,3-oxazinium salt; 1,3-thiazinium salt; N-acylacetylcarboxamide; N-acyl-β-mercaptocrotonamide
Studies on Pyrimidine Derivatives. XXXIII. Synthesis of Alkyl Pyrimidinyl Ketones by Means of Nitrosation of Alkylpyrimidines
Sakamoto, Takao,Sakasai, Takeji,Yoshizawa, Hiroshi,Tanji, Ken-Ichi,Nishimura, Sumiko,Yamanaka, Hiroshi
, p. 4554 - 4560 (2007/10/02)
The reaction of 4-alkylpyrimidines with propyl nitrite under acidic conditions followed by deoximation of the resulting ketoximes gave alkyl pyrimidinyl ketones in satisfactory yields.As compared with the direct oxidation of the alkylpyrimidines with sele
