83526-33-4 Usage
Uses
Used in Pharmaceutical Industry:
5-Hydroxyflecainide is used as an active metabolite for enhancing the antiarrhythmic effects of Flecainide. It contributes to the modulation of cardiac sodium channels, leading to a reduction in the rapid and slow inward sodium currents. This results in a decreased conduction velocity and an increased refractory period in cardiac tissues, which helps in the management and prevention of various types of arrhythmias.
Used in Cardiology:
5-Hydroxyflecainide is used as a therapeutic agent for the treatment of supraventricular and ventricular arrhythmias. Its electrophysiological properties allow it to effectively suppress abnormal electrical impulses in the heart, thereby restoring and maintaining a normal heart rhythm. This makes it a valuable component in the management of arrhythmic conditions such as atrial fibrillation, atrial flutter, and ventricular tachycardia.
Check Digit Verification of cas no
The CAS Registry Mumber 83526-33-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,5,2 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 83526-33:
(7*8)+(6*3)+(5*5)+(4*2)+(3*6)+(2*3)+(1*3)=134
134 % 10 = 4
So 83526-33-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H19F3N2O3/c16-15(17,18)9-23-13-5-4-11(21)7-12(13)14(22)20-8-10-3-1-2-6-19-10/h4-5,7,10,19,21H,1-3,6,8-9H2,(H,20,22)
83526-33-4Relevant academic research and scientific papers
Phenolic derivative
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, (2008/06/13)
A novel N-(2-piperidylmethyl)-2,2,2-trifluoroethoxy)benzamide and its pharmaceutically acceptable salts.
5-Benzyloxy or 5-hydroxy-2-(2,2,2-trifluoroethoxy)-N-(2-pyridylmethyl)benzamide
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, (2008/06/13)
Substituted 2-(trifluoroethoxy)benzamide, benzoic acid and benzoate compounds which are intermediates in the preparation of pharmaceutically active agents.
