83537-77-3Relevant academic research and scientific papers
Synthesis of the N-Terminal Amino Acid of the Nikkomycins I, J, X, and Z
Hass, Werner,Koenig, Wilfried A.
, p. 1615 - 1622 (2007/10/02)
A mixture of four stereoisomers of 2-amino-4-hydroxy-4-(5-hydroxy-2-pyridyl)-3-methylbutanoic acid (14), the N-terminal amino acid of the nikkomycin antibiotics could be synthesized in a twelve-step procedure.By comparison of 1H NMR spectra, mass spectra and of the gas chromatographic behaviour of various derivatives the constitution and relative configuration of the natural compound has been confirmed.
