83546-42-3 Usage
General Description
2'-Fluoro-5-ethylarabinosyluracil, also known as FEU, is a synthetic nucleoside analogue that is structurally related to the antiviral drug ribavirin. It has been studied for its potential antiviral activity against a wide range of viruses, including influenza, hepatitis C, and herpes simplex virus. FEU has been shown to inhibit viral replication by interfering with the synthesis of viral RNA, and it has demonstrated good potency and selectivity in in vitro and in vivo studies. Its unique chemical structure and potential for antiviral activity make FEU a promising candidate for further development as a therapeutic agent for the treatment of viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 83546-42-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,5,4 and 6 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 83546-42:
(7*8)+(6*3)+(5*5)+(4*4)+(3*6)+(2*4)+(1*2)=143
143 % 10 = 3
So 83546-42-3 is a valid CAS Registry Number.
83546-42-3Relevant articles and documents
A general synthesis of 2′-deoxy-2′-[18F]fluoro-1-β-D- arabinofuranosyluracil and its 5-substituted nucleosides
Alauddin, Mian M.,Conti, Peter S.,Fissekis, John D.
, p. 285 - 289 (2007/10/03)
Several 2′-deoxy-2′-[18F]fluoro-1-β-D- arabinofuranosyluracil derivatives have been synthesized. Coupling of 1-bromo-2-deoxy-2-[18F]fluoro-3,5-di-O-benzoyl-α-D- arabinofuranose 2 with protected uracil derivatives 3a-e followed by hydrolysis and high-performance liquid chromatography purification produced the radiolabeled nucleosides 4a-e in 15-30% yield (d. c.), > 99% radiochemical purity and 55.5-103.6 GBq/μmol specific activities. Copyright
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent
Mansuri,Ghazzouli,Chen,Howell,Brodfuehrer,Benigni,Martin
, p. 867 - 871 (2007/10/02)
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