83548-59-8

Upstream product

• 18593-47-0 2-benzyl-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one 
• 18593-47-0 2-benzyl-5,6-dimethylthieno[2,3-d]pyrimidin-4-(3H)-one 
• 140-29-4 phenylacetonitrile 
• 4815-24-1 2-amino-4,5-dimethyl-3-thiophenecarboxylic acid ethyl ester 
• 645-54-5 2-phenylthioacetamide 
• 103-81-1 Benzeneacetamide 

Downstream Products

• 401511-14-6 2-benzyl-4-[(2-hydroxy)ethyl]amino-5,6-dimethylthieno[2,3-d]pyrimidine 
• 1089813-89-7 2-benzyl-5,6-dimethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine 
• 1611471-57-8 4-(4-benzhydrylpiperazin-1-yl)-2-benzyl-5,6-dimethyl-4-thieno[2,3-d]pyrimidine 
• 83548-74-7 5-Benzyl-8,9-dimethyl-tetrazolo[1,5-c]thieno[3,2-e]pyrimidine 
• 83548-66-7 (2-Benzyl-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-yl)-hydrazine 

Relevant academic research and scientific papers

Microwave-assisted synthesis of potent PDE7 inhibitors containing a thienopyrimidin-4-amine scaffold

A series of novel thienopyrimidin-4-amines have been synthesized and evaluated as phosphodiesterase (PDE) inhibitors. A rationale for the observed selectivity against PDE7 has been obtained from molecular modelling studies on the most active compounds. This journal is the Partner Organisations 2014.

Microwave-Assisted Synthesis of Novel 5-Substituted-2,3-dihydroimidazo[1,2-c]thieno[3,2-e]pyrimidines

A novel, facile microwave-assisted route for the synthesis of imidazo[1,2-c]thieno[3,2-e]pyrimidines 4 in quantitative yields is reported. The intermediates 4-chlorothieno[2,3-d]pyrimidines 3 were synthesized under one-pot reaction conditions.

Synthesis and Biological Activity of Tetrazolothienopyrimidines

4-Hydrazinothienopyrimidines (VI) undergo cyclization with nitrous acid to give tetrazolothienopyrimidines (VII).The latter compounds have been screened for their analgesic and antiinflammatory activities.