83548-85-0

Upstream product

• 29976-82-7 1-(2-hydroxy-5-methylphenyl)-3-phenylpropane-1,3-dione 
• 4010-19-9 1-(2-benzoyloxy-5-methylphenyl)-ethanone 

Downstream Products

• 83548-89-4 2-(4-Bromo-1,5-diphenyl-1H-pyrazol-3-yl)-4-methyl-phenol 

Relevant academic research and scientific papers

An efficient synthesis of 3-bromoflavones under solvent free conditions using grinding technique

Selective bromination of 1-(2-hydroxyphenyl)-3-phenylpropane- 1,3-diones has been carried out with ammonium bromide and ammonium persulphate at room temperature using grinding technique under solvent free conditions to give 2-bromo derivatives which on cyclodehydration with p-toluenesulphonic acid under grinding conditions give 3-bromoflavones. Also, flavones on bromination using above mentioned conditions give 3-bromoflavones directly.

Selective halogenation of 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones using phase transfer catalysis and synthesis of 3-chloro- and 3-bromo-flavones

Selective chlorination and bromination of 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones have been achieved by their reaction with ammonium chloride/ammonium bromide and hydrogen peroxide in biphase medium using phase transfer catalysis.