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1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, (S)is a complex and unique carboxylic acid with a chiral (S)enantiomer. It features a spiro ring system and contains sulfur and nitrogen atoms in its backbone, which may contribute to its potential applications in various fields.
Used in Pharmaceutical Industry:
1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, (S)is used as a potential pharmaceutical compound for its unique structure and chiral nature, which may offer advantages in drug development and design.
Used in Agrochemical Industry:
1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, (S)is used as a potential agrochemical compound, where its unique structure and chiral nature could be beneficial in the development of new pesticides or other agricultural chemicals.
Used as a Building Block in Chemical Synthesis:
1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, (S)is used as a building block in the synthesis of other complex organic compounds, taking advantage of its unique structure and functional groups for creating novel molecules with specific properties.

83552-44-7

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83552-44-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 83552-44-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,5,5 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 83552-44:
(7*8)+(6*3)+(5*5)+(4*5)+(3*2)+(2*4)+(1*4)=137
137 % 10 = 7
So 83552-44-7 is a valid CAS Registry Number.

83552-44-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (8S)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid

1.2 Other means of identification

Product number -
Other names DIT001

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83552-44-7 SDS

83552-44-7Relevant academic research and scientific papers

Angiotensin Converting Enzyme Inhibitors: Spirapril and Related Compounds

Smith, Elizabeth M.,Swiss, Gerald F.,Neustadt, Bernard R.,McNamara, Paul,Gold, Elijah H.,et al.

, p. 1600 - 1606 (2007/10/02)

The synthesis of spirapril (5), spiraprilat (25), their RSS stereoisomers, and their glycyl (18b) and lysyl (36, 37) analogues is described.These compounds were evaluated in vivo for inhibition of angiotensin converting enzyme (ACE), and selected compounds were evaluated for in vitro ACE inhibition (spirapril ID50 16 μg/kg; spiraprilat IC50 0.8 nM, ID50 8 μg/kg).In anesthetized rats, iv, esters 5 and 36 are more potent than enalapril, and diacids 25 and 37 are more potent than enalaprilat in vitro.In the conscious rats, orally, 5 and enalapril (2) showed potent and sustained activity at doses of 0.03-1 and 0.1-1 mg/kg, respectively.From this work, spirapril was selected for clinical evaluation as an antihypertensive agent.

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