83553-60-0 Usage
Uses
Used in Pharmaceutical Industry:
4-(Methylthio)-1H-imidazole is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with diverse therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(Methylthio)-1H-imidazole is employed as a precursor in the production of agrochemicals, aiding in the creation of compounds that can enhance crop protection and yield.
Used in Organic Synthesis:
4-(Methylthio)-1H-imidazole is used as a building block in organic synthesis for its capacity to form a variety of complex organic compounds, contributing to the advancement of chemical research and development.
Used as a Reagent in Chemical Reactions:
4-(METHYLTHIO)-1H-IMIDAZOLE is utilized as a reagent to introduce the imidazole ring into other organic compounds, facilitating the synthesis of novel chemical entities with potential applications in various fields.
Used in Biological Research:
4-(Methylthio)-1H-imidazole is studied for its potential biological activities such as antioxidant, anti-inflammatory, and antimicrobial properties, indicating its use in the exploration of new therapeutic agents and treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 83553-60-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,5,5 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 83553-60:
(7*8)+(6*3)+(5*5)+(4*5)+(3*3)+(2*6)+(1*0)=140
140 % 10 = 0
So 83553-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2S/c1-7-4-2-5-3-6-4/h2-3H,1H3,(H,5,6)
83553-60-0Relevant academic research and scientific papers
HIGH-YIELDING SYNTHESES OF 4(5)-SUBSTITUTED IMIDAZOLES VIA ORGANOLITHIUM INTERMEDIATES. THE UTILITY OF SULPHONAMIDE N-PROTECTION AND SILICON-CONTAINING BLOCKING GROUPS
Carpenter, Andrew J.,Chadwick, Derek J.
, p. 2351 - 2358 (2007/10/02)
N-protection of imidazole as its N,N-dimethyl-sulphonamido derivative, and blocking of the 2-position with the triethylsilyl group permits regioselective 5-metallation with sec-butyl-lithium.The resulting organolithium intermediates react with a range of electrophiles and the products are easily deprotected to give the 4(5)-substituted NH-free imidazoles in good to excellent yields.Isolation of the silicon-blocked intermediate is unnecessary and, indeed, is disadvantageous to final yields, making the procedure attractively economical of time.
