835595-62-5 Usage
Molecular weight
291.36 g/mol
Structure
The compound has a piperidine ring, a carboxylic acid group, and a tert-butyl ester.
Usage
It is used in organic synthesis as a reagent and building block in the production of pharmaceuticals, agrochemicals, and other fine chemicals.
Stability
It is commonly used as a precursor in the synthesis of complex organic compounds due to its stability.
Reactivity
It is highly reactive and a versatile molecule for various chemical reactions.
Importance
Its unique structure and properties make it an important intermediate in the manufacturing of diverse chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 835595-62-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,5,5,9 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 835595-62:
(8*8)+(7*3)+(6*5)+(5*5)+(4*9)+(3*5)+(2*6)+(1*2)=205
205 % 10 = 5
So 835595-62-5 is a valid CAS Registry Number.
835595-62-5Relevant academic research and scientific papers
CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives
Imamura, Shinichi,Nishikawa, Youichi,Ichikawa, Takashi,Hattori, Taeko,Matsushita, Yoshihiro,Hashiguchi, Shohei,Kanzaki, Naoyuki,Iizawa, Yuji,Baba, Masanori,Sugihara, Yoshihiro
, p. 397 - 416 (2007/10/03)
Replacement of the 5-oxopyrrolidin-3-yl fragment in the previously reported lead structure with a 1-acetylpiperidin-4-yl group led to the discovery of a novel series of potent CCR5 antagonists. Introduction of small hydrophobic substituents on the central phenyl ring increased the binding affinity, providing low to sub-nanomolar CCR5 antagonists. The selected compound 11f showed excellent antiviral activity against CCR5-using HIV-1 replication in human peripheral blood mononuclear cells (EC50 = 0.59 nM) and an acceptable pharmacokinetic profile in dogs.
