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Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-AMINOHEPT-6-YNOIC ACID is used as a building block for the synthesis of bioactive compounds due to its terminal alkyne group, which facilitates the creation of novel pharmaceuticals with potential applications in various therapeutic areas.
Used in Antibacterial Applications:
(S)-2-AMINOHEPT-6-YNOIC ACID is used as an antibacterial agent, leveraging its unique structure and biological activity to combat bacterial infections. Its potential in this area is currently under investigation, with the aim of developing new treatments for bacterial diseases.
Used in Anticancer Applications:
(S)-2-AMINOHEPT-6-YNOIC ACID is used as an anticancer agent, with ongoing research exploring its potential to target and inhibit cancer cell growth. Its unique structure may offer new avenues for the development of cancer therapies.
Used in Medicinal Chemistry:
(S)-2-AMINOHEPT-6-YNOIC ACID is used as a research target in medicinal chemistry, where its properties are being studied to understand its interactions with biological systems and to develop new drugs based on its structure.
Used in Drug Development:
(S)-2-AMINOHEPT-6-YNOIC ACID is used in the drug development process, as its unique structure and potential biological activities make it a promising candidate for the creation of new pharmaceuticals with various therapeutic applications.

Upstream product

• 121704-07-2 2-(2-Chloro-acetylamino)-hept-6-ynoic acid 

Downstream Products

• 211054-06-7 (R)-2-(Toluene-4-sulfonylamino)-hept-6-ynoic acid methyl ester 

Relevant academic research and scientific papers

Nα-Fmoc-protected ω-azido- and ω-alkynyl-L- amino acids as building blocks for the synthesis of "clickable" peptides

The growing interest in the 1,4-disubstituted-1,2,3-triazolyl moiety as an amide bond surrogate and its formation through very mild, chemoselective, and bioorthogonal CuI-catalyzed Huisgen 1,3-dipolar [3+2] cycloaddition of an alkynyl to an azi

Pd-catalyzed cyclization reactions of acetylene-containing α-amino acids

Acetylene-containing amino acids, obtained in enantiopure form via an enzymatic resolution process, serve as versatile intermediates in the synthesis of various highly functionalized heterocycles. The key transformations, intramolecular OC- and NC-bond formation, proceed via Pd- catalysis.

Kinetic Resolution of Unnatural and Rarely Occuring Amino Acids: Enantioselective Hydrolysis of N-Acyl Amino Acids Catalyzed by Acylase I

Acylase I (aminoacylase; N-acylamino-acid amidohydrolase, EC 3.5.1.14, from porcine kidney and the fungus Aspergillus) is broadly applicable enzymatic catalyst for the kinetic resolution of unnatural and rarely occuring α-amino acids.Its enantioselectivity for the hydrolysis of N-acyl L-α-amino acids is nearly absolute, yet it accepts substrates having a wide range of structure and functionality.This paper reports the initial rates of enzyme-catalyzed hydrolysis of over 50 N-acyl amino acids and analogues, the stabilities of the enzymes in aqueous and aqueous/organic solutions, and the effects of different acyl groups and metal ions on the rates of enzymatic hydrolysis.Eleven α-amino and α-methyl α-amino acids were resolved on a 2-29-g scale.Crude L- and D-amino acid products had generally >90percent ee.The utility of resolved amino acids as chiral synthons was illustrated by the preparation of (R)- and (S)-1-butene oxide and the diastereoselective (cis:trans, 7-8:1) iodolactonization of three 2-amino-4-alkenoic acid derivatives.