83569-71-5Relevant academic research and scientific papers
AN APPROACH TO TAXODIONE INVOLVING BIOMIMETIC POLYENE CYCLIZATION METHODOLOGY
Johnson, William S.,Shenvi, Ashok B.,Boots, Sharon G.
, p. 1397 - 1404 (2007/10/02)
A novel synthesis of 11,12-dimethoxyabieta-8,11,13-triene (4), involving the biomimetic cyclization of allylic alcohol 5 is described.This represents a formal total synthesis of taxodione (1), a tumor-inhibitory diterpenoid quinone methide.Treatment of th
