835879-05-5

Upstream product

• 109-01-3 1-methyl-piperazine 
• 2516-95-2 5-chloro-2-nitrobenzoic acid 
• 51282-49-6 methyl 5-chloro-2-nitrobenzoate 

Downstream Products

• 1092931-97-9 C₁₂H₁₉N₃O 
• 835879-06-6 2-amino-5-(4-methylpiperazin-1-yl)benzoic acid 
• 188604-38-8 N-(4-chloro-phenyl)-5-(4-methyl-piperazin-1-yl)-2-nitro-benzamide 
• 188604-39-9 2-amino-N-(4-chloro-phenyl)-5-(4-methyl-piperazin-1-yl)-benzamide 

Relevant academic research and scientific papers

NEW COMPOUNDS

The present invention encompasses compounds of general Formula (I) wherein R2, R3, Q, W, X, Y and Z are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation

AMINOQUINOLINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS

Compounds of the general formula (I), and their salts, solvates, isomers (tautomers, desmotrops, optically active isomers) as well as the salts and solvates; are strong adenosine A3 receptor ligands preferably antagonists.

SUBSTITUTED QUINAZOLONES AS ANTI-CANCER AGENTS

The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.