835890-35-2Relevant academic research and scientific papers
Cycloiridation of α,β-unsaturated ketones, esters, and acetophenone
Li, Xingwei,Chen, Peng,Faller, Jack W.,Crabtree, Robert H.
, p. 4810 - 4815 (2005)
C-H activation of acetophenone and cyclic and acyclic α,β- unsaturated ketones or esters occurs with [IrH2(acetone) 2(PPh3)2]+. In the case of acyclic α,β-unsaturated ketones or esters, the β-C-H bond was activated to afford iridafuran hydrides as cyclometalation products. For cyclopentenone, a cyclic α,β-unsaturated ketone, the C-H activation affords an η5-hydroxycyclopentadienyl iridium hydride. The activation of the ortho C-H bonds in acetophenone affords orthometalated products structurally related to the iridafuran hydrides. Plausible mechanisms are proposed for reactions in each case. In particular, the formation of iridafurans is believed to proceed by a mechanism analogous to that previously proposed for the RuH 2(CO)(PPh3)3-catalyzed Murai reaction.
