83602-28-2

Upstream product

• 83562-28-1 1-benzyl-7-butyl-1-azaspirocyclo<5.5>undec-7-ene 
• 86817-86-9 O-acetyl-N-benzyldepentylperhydrohistrionicotoxin 
• 88204-70-0 1-Benzyl-7-butyl-9-trimethylsilanyloxy-1-aza-spiro[5.5]undec-8-ene 
• 83562-30-5 2-Butyl-3-<4-(p-tolylsulfonoxy)butyl>cyclohex-2-en-1-one 
• 83562-29-2 2-Butyl-3-(4-hydroxybutyl)-2-cyclohexen-1-one 
• 56459-18-8 2-butyl-3-ethoxy-2-cyclohexen-1-one 
• 85612-38-0 2-Butyl-3-<4-(p-tolylsulfonoxy)butyl>cyclohex-2-en-1-ol 
• 86817-84-7 1-Acetoxy-2-butyl-3-<4-(benzylamino)butyl>cyclohex-2-ene 
• 88204-71-1 1-benzyl-7-butyl-1-azaspiro<5.5>undec-7-en-9-one 
• 88204-72-2 1-benzyl-7-butyl-1-azaspiro<5.5>undec-7-en-9-ol 
• 77204-60-5 1-benzyl-1-azaspiro<5.5>undec-7-en-9-one 
• 88367-25-3 1-Acetoxy-2-butyl-3-<4-(p-tolylsulfonoxy)butyl>cyclohex-2-ene 

Downstream Products

• 55228-77-8 (6R,7R,8R)-7-Butyl-1-aza-spiro[5.5]undecan-8-ol 
• 86817-86-9 O-acetyl-N-benzyldepentylperhydrohistrionicotoxin 
• 86817-86-9 O-acetyl-N-benzyldepentylperhydrohistrionicotoxin 
• 55228-77-8 (+/-)-depentylperhydrohistrionicotoxin 
• 83562-31-6 (6RS,7SR,8SR)-7-n-Butyl-N-benzyl-1-azaspiro<5.5>undecan-8-ol 

Relevant academic research and scientific papers

A stereoselective approach to the azaspiro[5.5]undecane ring system using a conjugate addition/dipolar cycloaddition cascade: Application to the total synthesis of (±)-2,7,8-epi-perhydrohistrionicotoxin

(Chemical Equation Presented) An efficient stereocontrolled route to the spirocyclic perhydrohistrionicotoxin derivative (±)-2,7,8-epi- PHTx (4) is described. The reaction of 2-butyl-3-(methoxymethoxy)cyclohexanone oxime with 2,3-bis(phenylsulfonyl)-1,3-b

Synthesis of (+/-)-Depentylperhydrohistrionicotoxin

Palladium(0)-catalysed cyclisation of 3-acetoxy-1-(4-aminoalkyl)cyclohexenes provides convenient access to the 1-azaspiroundecane ring system found in the histrionicotoxins.Hydroboration of the 7-butyl derivative (4; R1 = Bun, R

Flexible Synthetic Approach to Histrionicotoxin Congeners. Formal Total Synthesis of (+/-)-Perhydrohistrionicotoxin

Conversion of 1-benzyl-1-azaspiroundec-7-en-9-one (7), readily available using simple organoiron chemistry, in six steps into (+/-)-depentylperhydrohistrionicotoxin (3) is reported.This compound has been previously reported as an intermediate for syn