83604-10-8Relevant academic research and scientific papers
Synthesis of novel ligands targeting phenazine biosynthesis proteins as a strategy for antibiotic intervention
Guttenberger, Nikolaus,Schlatzer, Thomas,Leypold, Mario,Tassoti, Sebastian,Breinbauer, Rolf
, p. 847 - 856 (2017/12/06)
Abstract: In this contribution, we report synthetic strategies towards potential ligands for the study of binding differences between PhzE, the first enzyme in the biosynthesis of phenazines, and the related enzyme anthranilate synthase. The ligands were
BRIEF SYNTHESES OF (+/-)-METHYL SHIKIMATE, (+/-)-METHYL EPISHIKIMATE AND STRUCTURAL VARIANTS
Campbell, Malcolm M.,Kaye, Aston D.,Sainsbury, Malcolm,Yavarzadeh, Roya
, p. 2461 - 2470 (2007/10/02)
Two brief syntheses of (+/-)-methyl shikimate are described in a strategy which offers potentially flexible access to a range of analogues.New intramolecular rearrangement reactions of epoxides derived from methyl 7-oxabicyclohept-3-ene 6-carboxylate and methyl bicyclohept-3-ene 6 carboxylate are described.
COMPLEMENTARY SHORT SYNTHESES OF (+/-)-METHYL SHIKIMATE
Campbell, Malcolm M.,Kaye, Aston D.,Sainsbury, Malcolm,Yavarzadeh, Roya
, p. 1629 - 1630 (2007/10/02)
Two syntheses of (+/-)-methyl shikimate from the adduct of furan and methyl acrylate are described.One requires the regioselective hydroxylation of (+/-)-5β,6β-dihydroxy-O,O-isopropylidene-2-methoxycarbonylcyclohexa-1,3-diene and the other cis-dihydroxyla
ON THE LEWIS ACID CATALYZED DIELS-ALDER REACTION OF FURAN. REGIO- AND STEREOSPECIFIC SYNTHESIS OF SUBSTITUTED CYCLOHEXENOLS AND CYCLOHEXADIENOLS.
Brion, Francis
, p. 5299 - 5302 (2007/10/02)
The cycloaddition between furan and some dienophiles can be greatly accelerated in the presence of a Lewis-Acid (i. e.ZnI2).The 7-oxabicycloheptyl system readily undergoes a base promoted β-elimination of the heteroatom bridge leading to subs
