83626-73-7Relevant academic research and scientific papers
Synthesis of ω-(4-aminophenylsulfonamido)alkyl disulfides and thiosulfates and their activity against dihydropteroate synthetase from sulfanilamide-resistant Neisseria gonorrhoeae
Foye,Kauffman,Suttimool
, p. 799 - 802 (1982)
A series of ω-(4-aminophenylsulfonamido)alkyl disulfides and ω-(4-aminophenylsulfonamido)alkanethiosulfates was synthesized from the reaction of p-acetamidobenzenesulfanilyl chloride and either the aminoalkyl disulfide dihydrobromide or the aminoalkyl bro
Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer's disease
Yahiaoui, Samir,Hamidouche, Katia,Ballandonne, Céline,Davis, Audrey,De Oliveira Santos, Jana Sopkova,Freret, Thomas,Boulouard, Michel,Rochais, Christophe,Dallemagne, Patrick
, p. 283 - 293 (2016/07/06)
5-HT4 receptor (5-HT4R) activation and blockade of the 5-HT6 receptor (5-HT6R) are known to enhance the release of numerous neurotransmitters whose depletion is implicated in Alzheimer's disease (AD). Furthermor
