836649-58-2Relevant academic research and scientific papers
The Synthesis and Testing of α-(Hydroxymethyl)pyrroles as DNA Binding Agents
Martyn, Derek C.,Abell, Andrew D.
, p. 1073 - 1077 (2004)
The α-(hydroxymethyl)pyrroles 16a and 16b were prepared and shown to be cytotoxic against the P388 cancer cell line. Ethyl 5-hydroxymethyl-1H-pyrrole-2-carboxylate 18 was inactive, demonstrating that an α-(hydroxymethyl)pyTrole group alone is not sufficient for activity. Compound 16b has been shown to bind to DNA with reasonable affinity.
Zeolite-Based Organic Synthesis (ZeoBOS) of Acortatarin A: First Total Synthesis Based on Native and Metal-Doped Zeolite-Catalyzed Steps
Wimmer, Eric,Borghèse, Sophie,Blanc, Aurélien,Bénéteau, Valérie,Pale, Patrick
supporting information, p. 1484 - 1489 (2017/02/10)
Similarly to polymer-supported assisted synthesis (PSAS), organic synthesis could be envisaged being performed by using zeolites, native or metal-doped, as heterogeneous catalysts. To illustrate this unprecedented Zeolite-Based Organic Synthesis (ZeoBOS),
