83670-49-9

Basic information

• Product Name: N-(4-bromobenzyl)hydroxylamine
• Synonyms: N-(4-bromobenzyl)hydroxylamine
• CAS NO: 83670-49-9
• Molecular Weight: 202.051
• Mol File: 83670-49-9.mol

Chemical Properties

• CAS DataBase Reference: N-(4-bromobenzyl)hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromobenzyl)hydroxylamine(83670-49-9)
• EPA Substance Registry System: N-(4-bromobenzyl)hydroxylamine(83670-49-9)

Safety Data

• Hazardous Substances Data: 83670-49-9(Hazardous Substances Data)

Upstream product

• 25062-46-8 4-bromobenzaldehyde Oxime 
• 1122-91-4 4-bromo-benzaldehyde 
• 25062-46-8 4-bromobenzaldehyde oxime 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Downstream Products

• 127598-63-4 N-(4-bromobenzyl)-4-methylaniline 

Relevant articles and documents

Metal- and Base-Free Room-Temperature Amination of Organoboronic Acids with N-Alkyl Hydroxylamines

We have found that readily available N-alkyl hydroxylamines are effective reagents for the amination of organoboronic acids in the presence of trichloroacetonitrile. This amination reaction proceeds rapidly at room temperature and in the absence of added metal or base, it tolerates a remarkable range of functional groups, and it can be used in the late-stage assembly of two complex units.

Phase-transfer catalysis for the synthesis of hydroxylamines from oximes using benzyltriethylammonium borohydride in methanol and under solid-phase conditions

Effective phase-transfer catalysis methodologies for the reduction of oximes to hydroxylamines by a selective and versatile reducing agent, benzyltriethylammonium borohydride (BTEABH), in methanol and under solid-phase conditions are presented.

A general one-pot, three-component mono N-alkylation of amines and amine derivatives in lithium perchlorate/diethyl ether solution

An efficient, general procedure for reductive monoalkylation of amines and amine derivatives with aldehydes is reported. Treatment of aldehydes with primary amines, secondary amines, O-trimethylsilylhydroxylamine, and N,N-dimethylhydrazine in lithium perc

AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF

The present application describes amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof of formula (I), or pharmaceutically acceptable salt forms thereof, wherein one of D and D' may be C(=NH)NH2 and the other H and J and J may be O or CH2, which are useful as inhibitors of factor Xa.

Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof

The present application describes amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof of formula I: or pharmaceutically acceptable salt forms thereof, wherein one of D and D' may be C(=NH)NH2 and the other H, and J1 and J2 may be O or CH2, which are useful as inhibitors of factor Xa.

Preparation of pyrrolidine and isoxazolidine benzamidines as potent inhibitors of coagulation factor Xa

The serine protease factor Xa is a critical enzyme in the blood coagulation cascade. Recently, the inhibition of factor Xa has begun to emerge as an attractive strategy for the discovery of novel antithrombotic agents. Here we describe pyrrolidine and isoxazolidine benzamidines as novel and potent inhibitors of factor Xa.

ALKYLATION OF AMINOHYDROXY ANION, DISSOCIATED SPECIES OF HYDROXYLAMINE

Aminohydroxy anion (3), dissociated species of hydroxylamine, was demontrated to be nucleophilic on oxygen atom from INDO calculation, and to give directly O-alkylhydroxylamines.