83675-82-5Relevant academic research and scientific papers
Pyridazinones. IV. Synthesis, antisecretory and antiulcer activities of urea derivatives
Yamada,Tsukamoto,Shimamura,et al.
, p. 209 - 214 (2007/10/02)
The synthesis of a series of 6-phenyl-3(2H)-pyridazinone derivatives having urea moiety via the addition of free amines into various isocyanates or carbamoyl chlorides was described. The gastric antisecretory activity of these compounds was evaluated usin
Pyridazinones. 2. Synthesis and Antisecretory and Antiulcer Activities of Thiourea and 2-Cyanoguanidine Derivatives
Yamada, Toshihiro,Nobuhara, Youichi,Shimamura, Hiroshi,Tsukamoto, Yoshitsugu,Yoshihara, Kazuo,et al.
, p. 373 - 381 (2007/10/02)
In an effort to develop new types of antiulcer agents, we synthesized a series of novel 2-- and 2--3-(2H)-pyridazinone derivatives.All target compounds were evaluated for gastric antisecretory activity in the
