83696-69-9

Basic information

• Product Name: 1(2H)-Isoquinolinone,2-propyl-(9CI)
• Synonyms: 1(2H)-Isoquinolinone,2-propyl-(9CI)
• CAS NO: 83696-69-9
• Molecular Formula: C12H13NO
• Molecular Weight: 187.23772
• Product Categories: QUINOLINONE
• Mol File: 83696-69-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1(2H)-Isoquinolinone,2-propyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Isoquinolinone,2-propyl-(9CI)(83696-69-9)
• EPA Substance Registry System: 1(2H)-Isoquinolinone,2-propyl-(9CI)(83696-69-9)

Safety Data

• Hazardous Substances Data: 83696-69-9(Hazardous Substances Data)

Usage

Description

1(2H)-Isoquinolinone,2-propyl-(9CI) is a chemical compound with the molecular formula C13H13NO, belonging to the isoquinolinone family of cyclic compounds characterized by the presence of a nitrogen atom in the ring. The unique 2-propyl group attached to the isoquinolinone ring endows this compound with distinct properties, which may hold potential for various applications, particularly in the pharmaceutical industry.

Uses

Used in Pharmaceutical Applications:
1(2H)-Isoquinolinone,2-propyl-(9CI) is used as a potential candidate in the pharmaceutical industry for its possible biological activities. 1(2H)-Isoquinolinone,2-propyl-(9CI) is being investigated for its anticancer properties, as isoquinolinone derivatives have shown promise in this area. Further research is necessary to explore its full potential and effects on different types of cancer.
Additionally, 1(2H)-Isoquinolinone,2-propyl-(9CI) may also be utilized in the development of anti-inflammatory and antimicrobial drugs, given the known properties of isoquinolinone derivatives in these areas. As with its anticancer potential, more research is required to confirm its efficacy and safety in these applications.
Used in Research and Development:
In the field of scientific research, 1(2H)-Isoquinolinone,2-propyl-(9CI) serves as a valuable compound for studying the structure-activity relationships of isoquinolinone derivatives. This knowledge can be applied to the design and synthesis of new drugs with improved pharmacological properties and reduced side effects.
Furthermore, the compound can be used as a reference material in the development of analytical methods and techniques for the detection and quantification of isoquinolinone derivatives in various samples, such as biological tissues, pharmaceutical formulations, and environmental samples.

Upstream product

• 491-30-5 1-isoquinolone 
• 57464-64-9 2-propylisoquinolin-2-ium iodide 
• 86377-01-7 2-propylisoquinolin-2-ium bromide 
• 83696-51-9 N-propyl N-vinyl thiobenzamide 
• 6426-92-2 N-propyl N-vinyl benzamide 
• 690256-02-1 2-(3-bromo-propyl)-2H-isoquinolin-1-one 
• 83696-63-3 propyl-2 isoquinoleine thione-1 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 119-65-3 isoquinoline 

Relevant articles and documents

Harnessing selective PET and EnT catalysis by chlorophyll to synthesizeN-alkylated quinoline-2(1H)-ones, isoquinoline-1(2H)-ones and 1,2,4-trioxanes

Photocatalytic syntheses of quinoline-2(1H)-ones, isoquinoline-1(2H)-ones and 1,2,4-trioxanes were achieved by selective photo-induced electron transfer (PET) and energy transfer (EnT), respectively, by chlorophyll under visible light irradiation. Quinoli

Carbene-catalyzed aerobic oxidation of isoquinolinium salts: Efficient synthesis of isoquinolinones

A mild and environmentally friendly carbene-catalyzed aerobic oxidation of isoquinolinium salts was successfully realized. Accordingly, a diverse set of isoquinolinones and phenanthridinones was efficiently prepared in good to excellent yields. The mechanistic study indicates that the formation of an aza-Breslow intermediate is the crucial step in this transformation. This reaction features ambient air as the sole oxidant and oxygen source, a broad substrate scope, and excellent functional-group tolerance and proceeds under mild reaction conditions. Furthermore, a highly efficient synthesis of bioactive molecules and natural products including N-methylcrinasiadine, N-isopentylcrinasiadine, N-phenethylcrinasiadine, isoindolo[2,1-b]isoquinolin-5(7H)-one, PJ-34, rac-Gusanlung D, rosettacin, 8-oxopseudopalmatine and ilicifoline B was accomplished.

Radical cyclizations to quinolone and isoquinolone systems under oxidative and reductive conditions

Radical cyclizations to quinolone and isoquinolone systems under Fenton-type and n-Bu3SnH-mediated conditions are described. For N-iodoalkylquinolones, ca. 3:1 mixtures of oxidative cyclization products at C-2, and unexpectedly at C-8, were obtained under both conditions. Five- or six-membered oxidative cyclization products were obtained from N-iodoalkylisoquinolones under Fenton-type conditions, whereas n-Bu 3SnH-mediated reactions gave products of reductive cyclization in the five, six, and seven-membered series.