83706-38-1Relevant academic research and scientific papers
Efficient copper-catalyzed N-arylation of sulfoximines with aryl iodides and aryl bromides
Sedelmeier, Joerg,Bolm, Carsten
, p. 6904 - 6906 (2005)
Two simple and inexpensive systems for copper-catalyed N-arylations of sulfoximines with aryl bromides and aryl iodides have been developed. Using 10 mol % of a copper(I) salt in combination with 20 mol % of a 1,2-diamine and Cs2CO3 provides N-arylated sulfoximines in high yields. Various functional groups and heteroatoms are tolarated. The method is complementary to the known protocols for N-arylations of sulfoximines, which require stoichiometric quantities of copper salts or cost-intensive palladium/BINAP catalysts.
Metal-Free, Phosphonium Salt-Mediated Sulfoximination of Azine N-Oxides: Approach for the Synthesis of N-Azine Sulfoximines
Aithagani, Sravan Kumar,Kumar, Mukesh,Yadav, Mahipal,Vishwakarma, Ram A.,Singh, Parvinder Pal
, p. 5886 - 5894 (2016/07/23)
Herein, we report a simple and metal-free method for the synthesis of N-azine sulfoximines by the nucleophilic substitution of azine N-oxides with NH-sulfoximines. The present method works at room temperature with wide functional group compatibility and gives several unprecedented N-azine sulfoximines. The reaction conditions were also found suitable with enantiopure substrates and furnished products without any racemization. It also finds an application in the sulfoximination of azine-based functional molecules such as 2,2′-bipyridine, 1,10-phenanthroline, and quinine.
Preparation and Reactions of Sulfonimidoyl Fluorides
Johnson, Carl R.,Bis, Kostaki G.,Cantillo, Jose H.,Meanwell, Nicholas A.,Reinhard, Michael F. D.,et al.
, p. 1 - 3 (2007/10/02)
Sulfonimidoyl fluorides have been prepared for the first time by treatment of sulfonimidoyl chlorides with various sources of fluoride ion.Sulfonimidoyl chlorides are reduced to sulfinamides with alkyllithium reagents; however, the corresponding fluorides
