83708-45-6Relevant academic research and scientific papers
Curtius rearrangement of ω-azido acid chlorides: Access to the corresponding ω-azido substituted amines and carbamates, useful building blocks for polyamine syntheses
Khoukhi, Mostafa,Vaultier, Michel,Benalil, Aziza,Carboni, Bertrand
, p. 483 - 487 (2007/10/03)
Treatment of ω-azido acid chlorides with trimethylsilyl azide affords ω-azido isocyanates which can be easily converted in good yields to the corresponding ω-azidoamines or ω-azidocarbamates. 1,3- and 1,4-diamine dihydrochlorides can then be prepared by catalytic hydrogenation or reductive alkylation with an organodichloroborane.
Use of tetrahydro-2H-1,3-oxazinones as aminopropylation agents
Poindexter,Strauss
, p. 1329 - 1338 (2007/10/02)
Treatment of tetrahydro-2H-1,3-oxazin-2-one (1) or the 3-methyl derivative 2 with aniline salts or thiophenols at 180°C affords the corresponding N-aryl-1,3-propanediamines 3 or 3-(arylthio)propanamines 4 in good yields.
