83710-73-0

Basic information

• Product Name: 1-chloro-2,6-diformylcyclohexene
• Synonyms: 1-chloro-2,6-diformylcyclohexene
• CAS NO: 83710-73-0
• Molecular Weight: 172.611
• Mol File: 83710-73-0.mol

Chemical Properties

• CAS DataBase Reference: 1-chloro-2,6-diformylcyclohexene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2,6-diformylcyclohexene(83710-73-0)
• EPA Substance Registry System: 1-chloro-2,6-diformylcyclohexene(83710-73-0)

Safety Data

• Hazardous Substances Data: 83710-73-0(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 83710-91-2 C₄₄H₃₄ClTe₂⁽¹⁺⁾*BF₄^(1-) 
• 63857-00-1 N-[(3-(anilinomethylene)-2-chloro-1-cyclohexen-1-yl)methylene]aniline hydrochloride 

Relevant articles and documents

Introduction of various substitutions to the methine bridge of heptamethine cyanine dyes: Via substituted dianil linkers

The unique optical properties of cyanine dyes have prompted their use in numerous applications. Heptamethine cyanines are commonly modified on the methine bridge after synthesis of a meso-chlorine containing cyanine. Herein, a series of heptamethine cyanines containing modified methine bridges were synthesized using substituted dianil linkers. Their optical properties including, molar absorptivity, fluorescence, and quantum yield were measured as well as their hydrophobic effects in polar buffer solution. It was shown that dyes containing cyclopentene in the methine bridge or a phenyl ring in the meso position display increased molar absorptivity while the increased flexibility of the dye containing a cycloheptene in the methine bridge prevented fluorescence.

Heptamethine cyanine dye and application thereof in accurate diagnosis and treatment of tumors

The invention relates to tumor-specific heptamethine cyanine near-infrared fluorescent dye and application thereof; the near-infrared fluorescent dye is ICG-03, may be spontaneously absorbed and accumulated by various human tumor cells, may specifically gather at tumor parts other than normal cells, and accordingly may serve for accurately diagnosing tumors. Molecules described herein have better optical features than ICG, are suitable for photodynamic therapy and tumor imaging, and are good in stability. The heptamethine cyanine near-infrared fluorescent dye of the invention is suitable for the accurate diagnosis and treatment of tumors.

Fluorescent Probe for Imaging Lymph Nodes

Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.