83727-33-7

Upstream product

• 83727-29-1 Methyl 2-<5-<3-(trifluoromethyl)phenyl>isoxazol-3-yl>benzoate 
• 402-24-4 3-(trifluoromethyl)styrene 
• 70001-61-5 Methyl 2-<5-<3-(trifluoromethyl)phenyl>-2-isoxazolin-3-yl>benzoate 
• 4122-56-9 methyl o-formylbenzoate 
• 69053-94-7 Methyl 2-(hydroximinomethyl)benzoate 
• 69053-95-8 o-Metohycarbonylbenzohydroximinoyl chloride 

Relevant academic research and scientific papers

Iron Promoted Ring Opening and Ring Closing Cascade (ROCC) Reaction of Ortho-Carboxy-Isoxazoles Leading to Isoindolinone Derivatives

An efficient and convenient route for the synthesis of various functionalized 3-alkylidene isoindolin-1-ones is presented. The synthesis involves the ring opening and ring closing cascade (ROCC) reaction of ortho-carboxy-isoxazole using Fe/NH4Cl. This is the first report for the synthesis of 3-alkylidene isoindolin-1-one using Fe/NH4Cl.

Nitrile Oxide Cycloaddtion Routes to 2-(Isoxazolyl)benzoates and 2-(1,2,4-Oxadiazol-3-yl)benzoates

Cycloaddition of aromatic nitrile oxides to methyl o-vinylbenzoate produced methyl 2-(3-aryl-2-isoxazolin-5-yl)benzoates; the isoxazolines were converted to methyl 2-(3-arylisoxazol-5-yl)benzoates.Reaction of the nitrile oxide from o-methoxycarbonylbenzohydroximinoyl chloride (11) with phenylacetylene, styrenes, and aromatic nitriles resulted in methyl 2-(5-phenylisoxazol-3-yl)benzoate, methyl 2-(5-aryl-2-isoxazolin-3-yl)benzoates (15) and methyl 2-(5-aryl-1,2,4-oxadiazol-3-yl)benzoates, respectively.The isoxazolines 15 were converted to the corresponding isoxazoles 16.

Aryl-3-isoxazole benzoates as plant growth regulants and herbicides

2-(5-Aryl or substituted aryl-3-isoxazolyl) benzoic acids or benzoates, e.g., 2-[5-[3-(trifluoromethyl)phenyl]-3-isoxazolyl] benzoic acid, and to their method of use as herbicides and plant growth regulants as well as to agricultural chemical compositions