83749-67-1Relevant academic research and scientific papers
Fused [d]pyridazin-7-ones
-
Page/Page column 22; 8, (2008/06/13)
The present invention is directed to fused [d]pyridazin-7-ones. The invention is also directed to methods for making and using the fused [d]pyridazin-7-ones. In particular, the compounds of the present invention may be effective in the treatment of diseases or disease states related to the activity of VEGFR2, MLK1 and CDK5 enzymes, including, for example, angiogenic disorders and neurodegenerative diseases.
SYNTHESIS OF 5H-PYRIDAZOINDOLES BY CONDENSATION OF 2-ACYLINDOLE-3-CARBOXYLIC ACIDS WITH HYDRAZINE
Zhungietu, G. I.,Zorin, L. M.,Gorgos, V. I.,Rekhter, M. A.
, p. 811 - 813 (2007/10/02)
5H-Pyridazoindol-1-ones were obtained by heating 2-acetylindole-3- or 2-aroylindole-3-carboxylic acids with hydrazine hydrate in ethylene glycol or alcohol. 1-Chloro-5H-pyridazoindoles are formed by treatment of 5H-pyridazoindol-1-one
