83750-08-7Relevant academic research and scientific papers
DICHLORODIISOPROPOXYTITANIUM - A CONVENIENT REAGENT FOR THE SELECTIVE TRANSFORMATIONS OF α,β-EPOXYCARBONYL COMPOUNDS
Sosnovskii, G. M.,Astapovich, I. V.
, p. 71 - 73 (2007/10/02)
Depending on the structure and the reaction conditions, α,β-epoxycarbonyl compounds isomerize selectively in the presence of dichlorodiisopropoxytitanium to α-diketones or undergo nucleophilic cleavage with the formation of the corresponding hydroxychloro ketones.
REACTION OF ACETYLOXIRANES WITH ACETONITRILE
Bubel', O. N.,Tishchenko, I. G.,Ptashnikov, Yu. L.
, p. 773 - 775 (2007/10/02)
2-Acetyloxiranes react with acetonitrile in the presence of equimolar amounts of Lewis acids.It was established that the use of boron trifluoride etherate or sulfuric acid as the catalyst leads to 2,7- and 3,6-diepoxy-1,5-dioxocanes, the use of aluminum trichloride, as well as stannic chloride, leads to the corresponding chlorohydrins, while the use of gaseous boron trifluoride leads to 2-oxazolines in satisfactory yields.It is shown that the reaction is regio- and stereospecific and that the resulting substituted 2-methyl-5-acetyl-2-oxazolines have a cis configuration.
