83773-86-8

Upstream product

• 83774-15-6 2-phenoxy-4-piperazin-1-ylpyrimidine dihydrochloride 
• 23680-84-4 2-chloro-6,7-dimethoxyquinazolin-4-amine 
• 83774-25-8 2-phenoxy-4-(4-formylpiperazin-1-yl)pyrimidine 
• 83774-24-7 4-(2-chloropyrimidin-4-yl)piperazine-1-carbaldehyde 

Relevant academic research and scientific papers

2,4-Diamino-6,7-dimethoxyquinazolines. 3. 2-(4-Heterocyclylpiperazin-1-yl) Derivatives as α1-Adrenoceptor Antagonists and Antihypertensive Agents

A series of 4-amino-6,7-dimethoxy-2-(4-heterocyclylpiperazin-1-yl)quinazolines (3) was prepared and screened for α-adrenoceptor affinity and antihypertensive activity.These quinazoline derivatives showed high binding affinity (ca. 10-10 M) and

4-Amino-6,7-dimethoxy-2-(4-heteroaryl-piperazino)quinazoline antihypertensives

2,4-Diaminoquinazoline compounds of the formula STR1 or a pharmaceutically acceptable salt thereof wherein R is a pyrimidinyl, pyrazinyl, pyridazinyl or triazinyl group linked to the piperazine ring by one of its carbon atoms, and optionally substituted b