83782-78-9

Basic information

• Product Name: 2-((cyclohexylthio)methyl)pyridine
• CAS NO: 83782-78-9
• Molecular Weight: 207.34
• Mol File: 83782-78-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-((cyclohexylthio)methyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((cyclohexylthio)methyl)pyridine(83782-78-9)
• EPA Substance Registry System: 2-((cyclohexylthio)methyl)pyridine(83782-78-9)

Safety Data

• Hazardous Substances Data: 83782-78-9(Hazardous Substances Data)

Upstream product

• 7133-37-1 cyclohexyl methyl sulfide 
• 51342-19-9 N-methoxypyridinium methyl sulfate 
• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 50729-68-5 sodium cyclohexanethiolate 

Relevant articles and documents

α-Heteroarylation of Thioethers via Photoredox and Weak Br?nsted Base Catalysis

We report the C-H activation of thioethers to α-thio alkyl radicals and their addition to N-methoxyheteroarenium salts for the redox-neutral synthesis of α-heteroaromatic thioethers. Studies are consistent with a two-step activation mechanism, where oxidation of thioethers to sulfide radical cations by a photoredox catalyst is followed by α-C-H deprotonation by a weak Br?nsted base catalyst to afford α-thio alkyl radicals. Further, N-methoxyheteroarenium salts play additional roles as a source of methoxyl radical that contributes to α-thio alkyl radical generation and a sacrificial oxidant that regenerates the photoredox catalytic cycle.