83785-94-8

Upstream product

• 2213-43-6 1-Aminopiperidine 
• 555-16-8 4-nitrobenzaldehdye 
• 110-89-4 piperidine 

Downstream Products

• 100010-83-1 p-Nitrophenyl-glyoxylsaeure-p-tolylsulfonamid-N,N-pentamethylenhydrazon 
• 112080-81-6 5-(p-Nitro-phenyl)-1-piperidino-5-(p-tolylsulfonamido)-3-(p-tolylsulfonyl)imidazolidin-2,4-dion 

Relevant academic research and scientific papers

Copper-catalyzed trifluoromethylation of N,N-dialkylhydrazones

Mild and practical: Trifluoromethylation of (hetero)aromatic aldehyde N,N-dialkylhydrazones was achieved at room temperature by using Togni's trifluoromethylation reagent under CuCl catalysis (see scheme). This simple reaction is believed to occur by a CF3-radical-transfer mechanism and yields useful trifluoromethylated building blocks. Copyright

Aza-enamines, VIII. - Electrophilic Substitution reactions at the Azomethine C-Atom of Aldehyde Dialkylhydrazones: Vilsmeier Formylation and Consecutive Reactions

The reaction of hydrazones 1 with the Vilsmeier reagent yields 3-phenyl-1,4,5-triaza-1,3-pentadienium salts according to their aza-enamine character.Hydrolysis of 2 gives 1-phenylglyoxal 1-dialkylhydrazones 3, which rearrange in acidic media to 1-phenylglyoxal 2-dialkylhydrazones 4.Compound 3h forms the dihydropyrroloimidazole 5 in boiling ethanol.Pyrrolotriazinium salt 6 is obtained by the reaction of 1b with the isolated Vilsmeier reagent from dimethylformamide/oxalyl chloride.