83802-72-6

Usage

General Description

6-fluoro-5-methoxyindan is a chemical compound with the molecular formula C10H11FO. It is a derivative of indane and contains a fluorine atom and a methoxy group on the carbon ring. This chemical may have potential applications in pharmaceutical research and drug development, as it is similar to other indane derivatives that have exhibited various biological activities. It is important to handle and use 6-fluoro-5-methoxyindan with caution, as its specific properties and potential hazards have not been fully studied or characterized. Overall, 6-fluoro-5-methoxyindan is a novel chemical compound with potential utility in the field of medicinal chemistry and pharmacology.

Upstream product

• 83802-70-4 3-(3-fluoro-4-methoxyphenyl)propionyl chloride 
• 83802-71-5 5-fluoro-6-methoxy-2,3-dihydro-1H-inden-1-one 

Downstream Products

• 2676865-61-3 6-fluoro-5-isopropyl-2,3-dihydro-1H-inden-4-amine 
• 2676865-60-2 6-fluoro-4-nitro-5-(prop-1-en-2-yl)-2,3-dihydro-1H-indene 
• 2676865-58-8 6-fluoro-4-nitro-2,3-dihydro-1H-inden-5-ol 
• 83802-73-7 6-fluoro-5-indanol 

Relevant academic research and scientific papers

SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS

Described herein are compounds of Formula (I), Formula (I-A), and Formula (I-B), solvates thereof, tautomers thereof, and pharmaceutically acceptable salts of the foregoing, Further described herein are methods of inhibiting NLRP3 using said compounds, and methods of and compositions useful in treating NLRP3-dependent disorders.

Synthesis and antianxiety activity of (ω-piperazinylalkoxy)indan derivatives

A series of (ω-piperazinylalkoxyl)indan derivatives has been synthesized and screened for potential antianxiety activities. The effect of structural modification of these molecules on activities has been systematically examined. Antianxiety activity was displayed by 5-[3-(4-phenyl-1-piperazinyl)propoxy]indan (2), 5-[3-(4-[4-fluorophenyl)-1-piperazinyl]propoxy]indan (8), 6-fluoro-5-[3-(4-phenyl-1-piperazinyl)propoxy]indan (33), and 6-methyl-5-[3-(4-phenyl-1-piperazinyl)propoxy]indan (42), as determined in antifighting and anti-morphine tests. These derivatives in antianxiety tests were equipotent or more potent than chloridazepoxide with less muscle-relaxant effect. They also showed weak neuroleptic-like action.