83836-33-3

Usage

Class

Benzothiophene carboxamides

Structure

Contains a trifluoromethyl group on the phenyl ring and an amino group attached to the benzothiophene backbone

Potential applications

Pharmaceuticals, agrochemicals, materials science

Uses

Building block or intermediate in the synthesis of various functionalized benzothiophene derivatives

Properties

Unique structure and potential biological or chemical activities
Further research and development needed to explore potential uses and properties

Upstream product

• 108-94-1 cyclohexanone 
• 98-16-8 3-trifluoromethylaniline 
• 1960-77-6 2-cyano-N-[3-(trifluoromethyl)phenyl]acetamide 
• 89733-20-0 2-Cyano-2-cyclohexylidene-N-(3-trifluoromethyl-phenyl)-acetamide 

Downstream Products

• 83822-31-5 3-(3-Trifluoromethyl-phenyl)-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one 

Relevant academic research and scientific papers

Optimization of 2-acylaminocycloalkylthiophene derivatives for activity against Staphylococcus aureus RnpA

Staphylococcus aureus is well-recognized to cause debilitating bacterial infections that are difficult to treat due to the emergence of antibiotic resistance. As such, there is a need to develop new antimicrobials for the therapeutic intervention of S. au

2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers

Three series of 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene and 2-amino-5,6,7,8-tetrahydrocyclohepta[b]thiophenes with 3-carboxylates and carboxamides have been prepared using the Gewald synthesis and evaluated as A1AR allosteric enhancers. The