83851-42-7

Basic information

• Product Name: LEUKOTRIENE F4
• Synonyms: LEUKOTRIENE F4;5S-HYDROXY-6R-(S-GAMMA-GLUTAMYLCYSTEINYL)-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID;L-cysteine, S-[1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl]-N-L-g-glutamyl-,[R-[R*,S*-(E,E,Z,Z)]]-;LEUKOTRIENE F4 (METHANOL SOLUTION);LTF4;S-[N-[(1R,2E,4E,6Z,9Z)-1-[(S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-L-γ-glutamyl]-L-cysteine;PYSODLWHFWCFLV-JMUMRLTGSA-N
• CAS NO: 83851-42-7
• Molecular Formula: C28H44N2O8S
• Molecular Weight: 568.72
• Mol File: 83851-42-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 872.8 °C at 760 mmHg
• Flash Point: 481.6 °C
• Appearance: /
• Density: 1.205 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: LEUKOTRIENE F4(CAS DataBase Reference)
• NIST Chemistry Reference: LEUKOTRIENE F4(83851-42-7)
• EPA Substance Registry System: LEUKOTRIENE F4(83851-42-7)

Safety Data

• Hazardous Substances Data: 83851-42-7(Hazardous Substances Data)

Usage

Uses

Leukotriene F4 is a cysteinyl-leukotriene exhibiting agonistic properties.

Definition

ChEBI: A leukotriene composed of (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid having (5S)-hydroxy and (6R)-(L-gamma-glutamyl L-cystein-S-yl) substituents.

InChI:InChI=1/C28H44N2O8S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-24(23(31)15-14-17-26(33)34)39-20-22(28(37)38)30-25(32)19-18-21(29)27(35)36/h6-7,9-13,16,21-24,31H,2-5,8,14-15,17-20,29H2,1H3,(H,30,32)(H,33,34)(H,35,36)(H,37,38)/b7-6-,10-9-,12-11+,16-13+/t21-,22-,23-,24?/m0/s1

Upstream product

• 83851-50-7 (S)-4-((R)-2-Mercapto-1-methoxycarbonyl-ethylcarbamoyl)-2-(2,2,2-trifluoro-acetylamino)-butyric acid methyl ester 
• 73466-12-3 Leukotriene A₄ methyl ester 
• 83851-62-1 (7E,9E,11Z,14Z)-(5S,6R)-5-Hydroxy-6-{(R)-2-methoxycarbonyl-2-[(S)-4-methoxycarbonyl-4-(2,2,2-trifluoro-acetylamino)-butyrylamino]-ethylsulfanyl}-icosa-7,9,11,14-tetraenoic acid methyl ester 

Relevant articles and documents

Structural analogs of leukotrienes C and D and their contractile activities

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