Basic information

Product Name: CHRYSOMYCIN B
Synonyms: 4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one;B,ChrysoMycin;ChrysoMycin M, VirenoMycin M, Albacarcin M;6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl- (9CI)
CAS NO:83852-56-6
Molecular Formula: C27H28O9
Molecular Weight: 496.509
EINECS: N/A
Product Categories: A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Antibiotics by Application;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Inhibits an EnzymeEnzyme Inhibitors by Enzyme;Mechanism of Action;R to;Spectrum of Activity;Topoisomerase II
Mol File: 83852-56-6.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 784°C at 760 mmHg
Flash Point: 265.9°C
Appearance: /solid
Density: 1.410
Vapor Pressure: 6.89E-26mmHg at 25°C
Refractive Index: 1.662
Storage Temp.: 2-8°C
Solubility: DMF: soluble
PKA: 8.59±0.20(Predicted)
CAS DataBase Reference: CHRYSOMYCIN B(CAS DataBase Reference)
NIST Chemistry Reference: CHRYSOMYCIN B(83852-56-6)
EPA Substance Registry System: CHRYSOMYCIN B(83852-56-6)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany: 3
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 83852-56-6(Hazardous Substances Data)

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SDS
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83852-56-6 Usage

Uses

Used in Anticancer Applications:
Chrysomycin B is used as an antitumor agent for its ability to suppress the growth of transplantable tumors in mice. It is a potent inhibitor of the catalytic activity of human topoisomerase II and may act as a photoactivated cross-linker of DNA to histones, contributing to its anticancer properties.
Used in Pharmaceutical Industry:
Chrysomycin B is used as a research compound for studying the mechanisms of action of antibiotics and their potential applications in cancer treatment. Its structural similarity to gilvocarcin V allows for investigations into DNA cross-linking with histone 3 and GRP78 when photoactivated by near-UV light, which could lead to the development of novel therapeutic strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 83852-56-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,8,5 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 83852-56:
(7*8)+(6*3)+(5*8)+(4*5)+(3*2)+(2*5)+(1*6)=156
156 % 10 = 6
So 83852-56-6 is a valid CAS Registry Number.

InChI:InChI=1/C27H28O9/c1-11-8-15-19(17(9-11)33-4)14-10-18(34-5)21-16(28)7-6-13(20(21)22(14)36-26(15)31)23-25(30)27(3,32)24(29)12(2)35-23/h6-10,12,23-25,28-30,32H,1-5H3/t12-,23+,24+,25+,27-/m1/s1

83852-56-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	Chrysomycin B

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83852-56-6 SDS

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