83861-61-4

Basic information

• Product Name: 20-carboxy-leukotriene B4
• Synonyms: 6,8,10,14-Heneicosatetraenedioicacid, 5,12-dihydroxy-, [S-[R*,S*-(E,Z,E,Z)]]-
• CAS NO: 83861-61-4
• Molecular Formula: C21H32 O6
• Molecular Weight: 380.48
• Mol File: 83861-61-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 635.1°C at 760 mmHg
• Flash Point: 351.9°C
• Appearance: /
• Density: 1.136g/cm³
• Vapor Pressure: 8.47E-19mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: 20-carboxy-leukotriene B4(CAS DataBase Reference)
• NIST Chemistry Reference: 20-carboxy-leukotriene B4(83861-61-4)
• EPA Substance Registry System: 20-carboxy-leukotriene B4(83861-61-4)

Safety Data

• Hazardous Substances Data: 83861-61-4(Hazardous Substances Data)

Usage

General Description

20-carboxy-leukotriene B4 is a metabolite derived from leukotriene B4, an inflammatory mediator involved in various immune responses. It is produced by the enzymatic addition of a carboxyl group to the 20th carbon of leukotriene B4, and acts as an antagonist to leukotriene B4 by competing for its receptors and inhibiting its pro-inflammatory effects. 20-carboxy-leukotriene B4 has been shown to possess anti-inflammatory properties and has potential therapeutic applications for the treatment of inflammatory diseases, such as asthma, rheumatoid arthritis, and inflammatory bowel disease. Its role in modulating immune responses and inflammation makes it an important target for drug development and research.

InChI:InChI=1/C21H32O6/c22-18(12-7-3-1-2-4-10-16-20(24)25)13-8-5-6-9-14-19(23)15-11-17-21(26)27/h3,5-9,13-14,18-19,22-23H,1-2,4,10-12,15-17H2,(H,24,25)(H,26,27)/b6-5-,7-3-,13-8+,14-9+/t18-,19-/m0/s1