83863-44-9 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-methoxyphenyl)-4-(p-tolylsulphonyl)piperazine is used as a potential therapeutic agent for mental health disorders due to its agonistic activity on serotonin 5-HT1A receptors. This activity may help in the treatment of conditions such as depression and anxiety.
1-(2-methoxyphenyl)-4-(p-tolylsulphonyl)piperazine is also used as a potential inhibitor of carbonic anhydrase, an enzyme involved in various physiological processes. Its inhibition may have implications in the development of medications for neurological disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 83863-44-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,8,6 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 83863-44:
(7*8)+(6*3)+(5*8)+(4*6)+(3*3)+(2*4)+(1*4)=159
159 % 10 = 9
So 83863-44-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H22N2O3S/c1-15-7-9-16(10-8-15)24(21,22)20-13-11-19(12-14-20)17-5-3-4-6-18(17)23-2/h3-10H,11-14H2,1-2H3
83863-44-9Relevant academic research and scientific papers
Base-free monosulfonylation of amines using tosyl or mesyl chloride in water
Kamal, Ahmed,Reddy, J. Surendranadha,Bharathi, E. Vijaya,Dastagiri
, p. 348 - 353 (2008/09/17)
A mild and efficient procedure has been developed for the monosulfonylation of various amines using mesyl or tosyl chlorides in water at room temperature to afford the corresponding sulfonamides in high yields.
