83863-63-2

Basic information

• Product Name: DIBENZOFURAN-2-SULFONIC ACID
• Synonyms: TIMTEC-BB SBB007690;DIBENZOFURAN-2-SULFONIC ACID;DIBENZOFURAN-2-SULPHONIC ACID MONOHYDRATE;2-DIBENZOFURANSULFONIC ACID;Dibenzo[b,d]furan-2-sulfonic acid;Dibenzofuran-2-sulphonic acid;Diphenylene oxide-2-sulphonic acid monohydrate;2-Dibenzofuranesulfonicacid
• CAS NO: 83863-63-2
• Molecular Formula: C₁₂H₈O₄S
• Molecular Weight: 248.25
• EINECS: 281-128-6
• Mol File: 83863-63-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 144-145°C
• Appearance: /Powder
• Density: 1.52 g/cm³
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 0.13±0.30(Predicted)
• Sensitive: Hygroscopic
• CAS DataBase Reference: DIBENZOFURAN-2-SULFONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DIBENZOFURAN-2-SULFONIC ACID(83863-63-2)
• EPA Substance Registry System: DIBENZOFURAN-2-SULFONIC ACID(83863-63-2)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 83863-63-2(Hazardous Substances Data)

Usage

General Description

Dibenzofuran-2-sulfonic acid is a chemical compound with the molecular formula C12H10O4S. It is a white crystalline powder that is insoluble in water but soluble in organic solvents. Dibenzofuran-2-sulfonic acid is used as a reagent in various chemical reactions and as a building block in the synthesis of pharmaceuticals, dyes, and other organic compounds. It has also been studied for its potential application in the treatment of wastewater and as a corrosion inhibitor. Additionally, dibenzofuran-2-sulfonic acid has been used as a pH indicator and in the production of fluorescent dyes.

InChI:InChI=1/C12H8O4S/c13-17(14,15)8-5-6-12-10(7-8)9-3-1-2-4-11(9)16-12/h1-7H,(H,13,14,15)/p-1

Upstream product

• 132-64-9 dibenzofuran 

Downstream Products

• 1623-92-3 4-phenoxyphenylsulfonyl chloride 
• 147224-77-9 dibenzofuran-2-sulfonic acid anilide 
• 203640-01-1 (R)-2-(Dibenzofuran-2-sulfonylamino)-3-(1H-indol-3-yl)-propionic acid benzyl ester 
• 23602-98-4 dibenzofuran-2-sulfonyl chloride 

Relevant articles and documents

Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 1. Bicyclo[2.2.1]heptane derivatives

Novel prostaglandin D2 (PGD2) receptor antagonists were synthesized as a potential new class of antiallergic agents having a bicyclo[2.2.1] heptane ring system with sulfonamide groups. Some of them exhibit extremely potent antagonism of the PGD2 receptor in radioligand binding and cAMP formation assays with IC50 values below 50 nM and much less antagonism of TXA2 and PGI2 receptors. These potent PGD2 receptor antagonists, when given orally, dramatically suppress various allergic inflammatory responses such as increased vascular permeability in allergic rhinitis, conjunctivitis, and asthma models. The excellent pharmacological profiles of PGD2 receptor antagonists, originally synthesized in our laboratories, are of potentially great clinical significance. This study also provides experimental evidence suggesting that PGD2 plays an important role in the pathogenesis of allergic diseases.

Synthesis of aromatic sulfonyl chlorides - monomers for sulfur-containing polycondensation polymers

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