83867-80-5Relevant academic research and scientific papers
Direct synthesis of imines from alcohols and amines with liberation of H2
Gnanaprakasam, Boopathy,Zhang, Jing,Milstein, David
supporting information; experimental part, p. 1468 - 1471 (2010/05/02)
"Chemical equation presented" A clean sweep: Aryl and aliphatic mines can be synthesized directly and efficiently from alcohols and amines under mild, neutral conditions with the liberation of only molecular hydrogen and water (see scheme; R=isopropyl, tert-butyl). This general, environmentally benign reaction is catalyzed by a de-aromatized ruthenium PNP pincer complex (0.2 mol%), and can proceed in toluene under an inert atmosphere or under air.
