83867-97-4

Basic information

• Product Name: methyl 4,4-dimethyl-3-phenylpentanoate
• CAS NO: 83867-97-4
• Molecular Weight: 220.312
• Mol File: 83867-97-4.mol

Chemical Properties

• CAS DataBase Reference: methyl 4,4-dimethyl-3-phenylpentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4,4-dimethyl-3-phenylpentanoate(83867-97-4)
• EPA Substance Registry System: methyl 4,4-dimethyl-3-phenylpentanoate(83867-97-4)

Safety Data

• Hazardous Substances Data: 83867-97-4(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 140-10-3 (E)-3-phenylacrylic acid 
• 677-22-5 tert-butylmagnesium chloride 
• 594-19-4 tert.-butyl lithium 
• 2259-30-5 tert-butylmagnesium bromide 
• 103-26-4 Methyl cinnamate 

Relevant articles and documents

Addition of organolithium reagents to cinnamic acids

Reaction of tert-butyllithium with p- and m-substituted cinnamic acids at low temperature affords mixtures of 1,4- and 1,3-addition products, whose composition depend on the nature of the substituents. Electron-donating and electron-withdrawing groups favour 1,4- and 1,3-additions, respectively. Linear correlations are obtained with electronic effect and with radical substituent constants.

Contrasting behaviour of (E)-3-(trimethylsilyl)- and (E)-3-phenylpropenoic acids towards n-butyl- and tert-butyllithium

The title compounds 2 and 9 react with tert-buthyllithium to give considerable amounts of 'anti-Michael' adducts 3 and 10, respectively, in which the tert-butyl group is bonded to C-2.A single-electron-transfer (SET) mechanism is proposed for these reacti

REGIOSPECIFIC ADDITION OF ORGANOCOPPER REAGENTS TO α,β-UNSATURATED ESTERS

Mixed cuprates ArSCu(RMgX)n add rapidly to crotonates and cinnamates to give high yields of Michael adducts.Cuprates of methyl, ethyl, isopropyl, t-butyl, phenyl and vinyl were used.Crotonates give much higher yields of adducts with cuprates using 2-methoxythiophenoxide as a ligand than with those using thiophenoxide.