83873-17-0

Basic information

• Product Name: (9β,11β)-Epoxy FluoroMetholone Acetate
• Synonyms: (9β,11β)-Epoxy FluoroMetholone Acetate;(6α,9β,11β)-17-(Acetyloxy)-9,11-epoxy-6-Methylpregna-1,4-diene-3,20-dione
• CAS NO: 83873-17-0
• Molecular Formula: C24H30O5
• Molecular Weight: 398.492
• Product Categories: Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
• Mol File: 83873-17-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: (9β,11β)-Epoxy FluoroMetholone Acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (9β,11β)-Epoxy FluoroMetholone Acetate(83873-17-0)
• EPA Substance Registry System: (9β,11β)-Epoxy FluoroMetholone Acetate(83873-17-0)

Safety Data

• Hazardous Substances Data: 83873-17-0(Hazardous Substances Data)

Usage

Uses

An impurity of Fluorometholone Acetate (F593150).

Upstream product

• 130145-14-1 C₂₄H₃₀O₄ 
• 108-22-5 Isopropenyl acetate 
• 83873-16-9 6α-methyl-9,11β-epoxy-17α-hydroxy-pregna-1,4-diene-3,20-dione 

Relevant articles and documents

Fluorometholone, fluorometholone acetate, and preparation method thereof

The invention discloses fluorometholone, fluorometholone acetate, and a preparation method thereof. According to the preparation method, a compound represented by a formula (II) is taken as a raw material, the compound carries out de-chlorination reaction, esterification reaction, methenylation reaction, hydrogenation reaction, fermentation de-hydrogenation reaction, epoxidation reaction, and ring-opening reaction in sequence to obtain derivatives of fluorometholone; and fluorometholone derivatives carry out hydrolysis to obtain fluorometholone. The preparation method has the advantages of short synthesis route, high yield, low raw material cost, easily available raw materials, simple and convenient purification, high product purity, and strong technological operability, is suitable for industrial production, and has a high industrialization value.