83876-50-0 Usage
Description
(5R,6S)-12-methyl-5,6-dihydrobenzo[a]acridine-5,6-diol is a dihydrobenzo[a]acridine derivative with a molecular formula of C19H15NO2. It features a methyl group at the 12th position and hydroxyl groups at the 5th and 6th positions. (5R,6S)-12-methyl-5,6-dihydrobenzo[a]acridine-5,6-diol has potential biological activity and is considered an important intermediate in the synthesis of other pharmaceuticals or natural products. Its unique 3D structure and chemical properties make it a promising candidate for further research in medicinal chemistry and drug development.
Uses
Used in Pharmaceutical Synthesis:
(5R,6S)-12-methyl-5,6-dihydrobenzo[a]acridine-5,6-diol is used as an intermediate in the pharmaceutical industry for the synthesis of other pharmaceuticals or natural products. Its unique structure and potential biological activity make it a valuable compound for developing new drugs with specific therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (5R,6S)-12-methyl-5,6-dihydrobenzo[a]acridine-5,6-diol is used as a subject of study to explore its potential biological activities and understand its interactions with various biological targets. This research can lead to the discovery of new drug candidates or the optimization of existing ones.
Used in Drug Development:
(5R,6S)-12-methyl-5,6-dihydrobenzo[a]acridine-5,6-diol is also used in drug development as a potential candidate for the treatment of various diseases. Its unique chemical properties and potential biological activity make it an interesting compound to investigate for its efficacy and safety in preclinical and clinical trials.
Check Digit Verification of cas no
The CAS Registry Mumber 83876-50-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,8,7 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 83876-50:
(7*8)+(6*3)+(5*8)+(4*7)+(3*6)+(2*5)+(1*0)=170
170 % 10 = 0
So 83876-50-0 is a valid CAS Registry Number.
83876-50-0Relevant articles and documents
Synthesis and carcinogenic activity of oxidized benzacridines: Potential metabolites of the strong carcinogen 7-methylbenz[c]acridine and of the inactive isomer 12-methylbenz[a]acridine
Croisy Delcey,Croisy,Zajdela,Lhoste
, p. 303 - 306 (1983)
The synthesis of 15 compounds related either to the benz[c]acridine or to the benz[a]acridine series is reported. Spectral data, i.e., NMR and EI fragmentation are given. These compounds were tested for carcinogenic activity in mice of the XVIInc/Z strain by subcutaneous injection. Only three weak carcinogens were detected 5,6-dihydro-5,6-dihydroxy-12-methylbenz[a]acridine, 3-methoxy 7-methylbenz[c]acridine, and 4-acetoxy-7-methylbenz[c]acridine. These results are discussed with consideration to the data previously obtained with other benzacridines and condensed quinolines.
