83876-62-4

Basic information

• Product Name: 4-Acetoxy-7-methylbenz(c)acridine
• Synonyms: 4-Acetoxy-7-methylbenz(c)acridine;7-Methylbenz[c]acridin-4-ol acetate
• CAS NO: 83876-62-4
• Molecular Formula: C20H15 N O2
• Molecular Weight: 301.36
• Mol File: 83876-62-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 442.47°C (rough estimate)
• Flash Point: 268.4°C
• Appearance: /
• Density: 1.1858 (rough estimate)
• Vapor Pressure: 6.41E-11mmHg at 25°C
• Refractive Index: 1.5180 (estimate)
• CAS DataBase Reference: 4-Acetoxy-7-methylbenz(c)acridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Acetoxy-7-methylbenz(c)acridine(83876-62-4)
• EPA Substance Registry System: 4-Acetoxy-7-methylbenz(c)acridine(83876-62-4)

Safety Data

• Hazardous Substances Data: 83876-62-4(Hazardous Substances Data)

Usage

Safety Profile

Questionable carcinogen withexperimental tumorigenic data. When heated todecomposition it emits toxic fumes of NOx.

InChI:InChI=1/C20H15NO2/c1-12-14-6-3-4-8-18(14)21-20-15(12)10-11-16-17(20)7-5-9-19(16)23-13(2)22/h3-11H,1-2H3

Upstream product

• 83876-54-4 4-methoxy-7-methyl-5,6-dihydrobenzacridine 
• 83897-14-7 4-methoxy-7-methylbenzacridine 
• 25384-14-9 2-aminoacetophenone hydrochloride 
• 33892-75-0 5-Methoxy-1-tetralone 
• 108-24-7 acetic anhydride 
• 83876-59-9 4-hydroxy-7-methylbenzacridine 

Relevant articles and documents

Synthesis and carcinogenic activity of oxidized benzacridines: Potential metabolites of the strong carcinogen 7-methylbenz[c]acridine and of the inactive isomer 12-methylbenz[a]acridine

The synthesis of 15 compounds related either to the benz[c]acridine or to the benz[a]acridine series is reported. Spectral data, i.e., NMR and EI fragmentation are given. These compounds were tested for carcinogenic activity in mice of the XVIInc/Z strain by subcutaneous injection. Only three weak carcinogens were detected 5,6-dihydro-5,6-dihydroxy-12-methylbenz[a]acridine, 3-methoxy 7-methylbenz[c]acridine, and 4-acetoxy-7-methylbenz[c]acridine. These results are discussed with consideration to the data previously obtained with other benzacridines and condensed quinolines.