83877-77-4Relevant academic research and scientific papers
Stereoselective Synthesis of (Z)- and (E)-1,3-Alkadienes from Aldehydes Using Organotitanium and Lithium Reagents
Ikeda, Yoshihiko,Ukai, Junzo,Ikeda, Nobuo,Yamamoto, Hisashi
, p. 723 - 730 (2007/10/02)
titanium reagent generated easily from allyldiphenylphosphine condenses with aldehydes to give (Z)-1,3-alkadienes in a highly regio- and stereoselective manner.In contrast, lithiated allyldiphenylphosphine oxide condenses with aldehydes to give (E)-1,3-alkadienes directly and stereoselectively in good yield.Similarly, lithiated (1-buten-3-yl)diphenylphosphine oxide condenses with aldehydes to give (E)-3-methyl-1,3-alkadienes.
Selective Condensation of titanium Reagent with Carbonyl Compounds
Furuta, Kyoji,Ikeda, Yoshihiko,Meguriya, Noriyuki,Ikeda, Nobuo,Yamamoto, Hisashi
, p. 2781 - 2790 (2007/10/02)
titanium reagent generated easily from allyl ethyl sulfides condensed with aldehydes to give erythro-β-hydroxy sulfides in highly regio- and stereoselective manner.In contrast, crotyl ethyl sulfide reacted with aldehydes affording δ-hydroxy vinyl sulfide exclusively.The substitution pattern of the starting sulfide can have a pronounced effect on the selectivity in this condensation reaction, erythro-β-Hydroxy sulfide obtained was transfromed stereoselectively to the trans-vinyloxirane or 1,3-alkadiene.
DIRECT, STEREOSELECTIVE SYNTHESIS OF EITHER E- OR Z-1,3-DIENES
Ukai, Junzo,Ikeda, Yoshihiko,Ikeda, Nobou,Yamamoto, Hisashi
, p. 4029 - 4032 (2007/10/02)
New synthetic methods for the preparation of Z- or E-1,3-dienes are described.
