83881-59-8

Basic information

• Product Name: (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride
• Synonyms: (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride;Cetirizine IMpurity C;Acetic acid, 2-[2-[4-[(2- chlorophenyl)phenylMethyl]-1- piperazinyl]ethoxy]-;Cetirizine Dihydrochloride impurity C
• CAS NO: 83881-59-8
• Molecular Formula: C21H27Cl3N2O3
• Molecular Weight: 461.80968
• Mol File: 83881-59-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 536.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.237±0.06 g/cm3(Predicted)
• PKA: 3.46±0.10(Predicted)
• CAS DataBase Reference: (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride(83881-59-8)
• EPA Substance Registry System: (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride(83881-59-8)

Safety Data

• Hazardous Substances Data: 83881-59-8(Hazardous Substances Data)

Relevant articles and documents

2-[4-(Diphenylmethyl)-1-piperazinyl]-acetic acids and their amides

New 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acids, their amides and their salts, processes for the preparation thereof and therapeutic compositions. These compounds have the formula STR1 wherein Y=--OH or --NH2 ; X and X'=H, halogen, alkoxy or trifluoromethyl; m=1 or 2 and n=1 or 2. The amides of the 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acids are prepared either by reacting a 1-(diphenylmethyl)-piperazine with an omegahaloacetamide, or by reacting an alkali metal salt of an omega-[4-(diphenylmethyl)-1-piperazinyl]-alkanol with a 2-haloacetamide, or yet by reacting ammonia with a halide or alkyl ester of a 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acid, whereas the 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acids are prepared by hydrolyzing the corresponding amide or lower alkyl ester. These compounds have in particular an antiallergic, spasmolytic and antihistaminic activity.