83883-02-7Relevant articles and documents
THE BIOSYNTHESIS OF KAURENOLIDE DITERPENOIDS BY GIBBERELLA FUJIKUROI
Beale, Michael H.,Bearder, John R.,Down, Graham H.,Hutchinson, Michael,MacMillan, Jake,Phinney, Bernard O.
, p. 1279 - 1288 (2007/10/02)
The biosynthesis of 7β-hydroxy- and 7β,18-dihydroxy-kaurenolides from ent-kaur-16-en-19-oic acid has been investigated by incubating unlabelled and labelled putative intermediates with resuspension cultures of Gibberella fujikuroi.The results eliminate pathways which require the loss of oxygen from the 19-oic acid and indicate that the likely pathway is via ent-kaura-6,16-dien-19-oic acid and its ent-6α,7α-epoxide.Key Word Index - Gibberella fujikuroi; resuspension cultures; mutant B1-41a; kaurenoid biosynthesis; 7β-hydroxykaurenolide.